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Maria A. Landin


Maria A. Landin

University of Oslo, Norway

Biography

Dr Maria A. Landin is a toxicologist, specialized in toxicogenomics, working with Prof Harald Osmundsen at the institute for Oral Biology. During her PhD, she investigated and mapped the global gene expression in murine tooth buds using molecular biological methods. This lead to creation of a microarray database (68 microarrays) entailing 16 time points of murine tooth development from the embryonic day 11th up to 7 days post-partum (E11.5- P7). During her Dr’s degree she aquired knowledge and skills in molecular biological techniques such as microarrays, real-time RT-PCR, isolation of proteins or RNA / DNA from tissues or cells. She also masters various immunological techniques and have extensive experience in animal experiments and microdissection. She established In Situ hibridisering (Ribo-and oligoprober) at the institute and participated in several projects looking at the effects of brominated and / or perfluorinated flame retardants in wild type and knockout mice. She also colaborated with the biofilm groupe at the institute, where microarrays with up to 30K oligo were used to assess the toxicity of furanone in vivo.Currently Dr.Landin researches on the rolle microRNAs (miRNAs) in the regulation of the murine transcriptome using loss of function studies.

Abstract

Abstract : Mapping the global gene expression during tooth development may provide new bio-therapeutics tools in dentistry