Salivary Diagnostics and Oral Biomarkers

Salivary diagnostics and oral biomarkers of saliva as a diagnostic tool in modern dentistry. Salivary diagnostics and oral biomarkers are emerging fields in dentistry that utilize saliva as a non-invasive, accessible medium to detect, monitor, and predict oral and systemic diseases. Saliva contains a wealth of biological molecules, including proteins, enzymes, hormones, DNA, and RNA, which can serve as biomarkers for conditions such as oral cancers, periodontal disease, systemic infections, autoimmune disorders, and metabolic diseases. By analyzing these biomarkers, clinicians can gain insights into disease onset, progression, and patient response to treatment without the need for more invasive procedures like blood tests or biopsies.

Advances in molecular biology, biosensors, and lab-on-a-chip technologies have enhanced the sensitivity, specificity, and speed of salivary diagnostic tests, enabling point-of-care applications and personalized medicine approaches. Salivary diagnostics offer the potential for early detection, risk assessment, and monitoring of oral and systemic health, transforming preventive care and clinical decision-making. By bridging oral health with systemic health, this field underscores the growing importance of saliva as a diagnostic tool in modern dentistry.

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