Meera Avadhani
Title: Efficacy of Pomegranate extract based mouth rinse in patients with gingivitis as an adjunct to supragingival scaling - A Randomized controlled clinical trial.
Biography
Biography: Meera Avadhani
Abstract
Background & Objectives Plant alkaloids are being widely explored in the field of medicine, considering their lesser side effects and proven medicinal properties. The present study is designed to bring out the effects of pomegranate extract based mouth rinse in gingivitis patients as an adjunct to supragingival scaling. Methods 45 subjects diagnosed with chronic gingivitis were recruited into the study. Following baseline data collection in the form of Plaque index, Gingival Index, MDA and Thiol levels in saliva and GCF were evaluated. Supragingival scaling was performed in all the subjects and later divided in to 3 groups of 15 subjects each based on the different mouth rinses ascertained namely, distilled water group, 0.2% Chlorhexidine group and the test group. After a follow-up period of 1 month, the subjects were recalled for final data collection. Results The mean Plaque scores in the test group(1.01±0.17) as well as the 0.2% Chlorhexidine group(1.04±0.24 ) were significantly lesser when compared with the distilled water group(1.72±0.14). There was a greater reduction in the gingival index in the 0.2%Chlorhexidine group(52.22%) and the test group(59.07%) when compared with the distilled water group(17.04%). There was a greater reduction in the salivary and GCF MDA levels in the test group(54.04±13.71&69.28±12.54 ) and 0.2% Chlorhexidine group(56.54±27.01&43.64±20.2) when compared with distilled water group(32.82±14.13&21.62±24.03). The mean salivary and GCF Thiol levels at the end of 1 month follow-up period was found to be (240.00±143.48 & 274±89.35) for the distilled water group, (240.00±124.38&254.67±141.10) for the 0.2% Chlorhexidine group and (431.33±123.97& 449.33±153.41) for the test group respectively. Interpretation & Conclusion The present study which lasted for 1 month provided evidence for the additional benefits of mouth rinses used as an adjuvant in maintaining better oral hygiene. Pomegranate based mouth rinse provided improved oral hygiene and decreased gingival inflammation as compared to the control groups. Keywords : Punica granatum; Clorhexidine gluconate; Gingivitis; Anti-oxidants; Pro-oxidants; Dental Plaque