Siti Rusdiana Puspa Dewi
University of Sriwijaya, Indonesia
Title: Anticariogenic Effect of Gambir Extract on Enamel Tooth Surface Exposed by Stretococcus Mutans
Biography
Biography: Siti Rusdiana Puspa Dewi
Abstract
Introduction. Dental caries is the most common problem in many nations in the world, especially in Indonesia. Elimination of bacteria as one of caries causal can be done in many ways, one of them is using gambir plant extract. Gambir has chemical compounds like catechin and tannin, which have anticariogenic effect. The aim of this study was to determine anticariogenic effect of gambir extract on enamel tooth surface exposed by Streptococcus mutans.
Methods. An experimental study, in vitro, had been conducted in Integrated Laboratory Pasca Sarjana Unsri, Province’s Health Laboratory of South Sumatera, dan Metalurgy’s Laboratory of Engineering Faculty of University of Indonesia, and held on March to April 2015. There were 35 first and second upper premolar samples and divided into 5 groups; each groups using 40%, 50%, 60% gambir extract, negative control or placebo, and positive control (using cefadroxyl 500mg). Data were analyzed by using SPSS 22 vers.
Results. The results showed that 60% gambir extract had equal effect of reducing the decline of micropores in enamel topography to cefadroxyl 500 mg, 50% gambir extract had equal effect in reducing the decline of calcium’s weight to cefadroxyl 500 mg and had dose-dependent effect, 40% gambir extract had equal effect in lowering colonies of Streptococcus mutans to cefadroxyl 500 mg, and had dose-dependent effect.
Conclusion. It can be concluded that 60% gambir extract has equal anticariogenic effect to cefadroxyl 500 mg.