Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 24th International Conference on Dentistry & Oral Care Dubai, UAE.

Day 1 :

Keynote Forum

Donald J Ferguson

European University College, UAE

Keynote: Augmented Corticotomy with Orthodontics for Accelerated Tooth Movement
Dentistry 2017 International Conference Keynote Speaker Donald J Ferguson photo
Biography:

Dr. Ferguson is Professor of Orthodontics and Dean, European University College at Dubai Healthcare City, United Arab Emirates. He is formerly Professor and Chair of Orthodontics at Boston University and has held the positions of Executive Director, Center for Advanced Dental Education and Associate Dean for Dental Education, Saint Louis University, and Chair of Orthodontics and Director, Advanced Orthodontic Training Program, Marquette University. Dr. Ferguson is a diplomate of the American Board of Orthodontics (ABO) and past president of the EH Angle Society, Midwest Component. He served as a senior Fulbright scholar (a US national scholar award) at Alexandria University, Egypt, and has lectured extensively at university, regional, national and international forums. He received all of his professional dental degrees in the USA. Research interests include accelerated  tooth movement. He has authored over 100 articles and abstracts for professional journals and publications as well as contributed chapters to several textbooks.                       

Abstract:

Periodontally Accelerated Osteogenic Orthodontics (PAOO) combines alveolar decortication plus augmentation grafting technique to accelerated orthodontic tooth movement. Fixed orthodontic appliances are placed followed within 1 week by full thickness flap surgery and scaring of facial-lingual alveolar cortices. The patient is seen every 2 weeks following the procedure. Rapid tooth movement results from the transient demineralization-remineralization (osteopenia) produced within the alveolus, i.e. increased bone turnover. Benefits of PAOO therapy include: 1) active orthodontic treatment times averaging 6 months, 2) greater scope of malocclusion treatment, 2) greater stability of clinical outcomes and less relapse, and 3) increased alveolar volume and enhanced periodontal health.

Tensional integrity or “prestress” keeps hydrostatically contained dento-alveolar tissues sensitive to and prepared for changes in the biomechanical environment. Sustained orthodontic forces translated at nano-level in the multiple microenvironments involved in tooth movement are reflected at all length scales including the organ-level. The biomechanical stresses introduced by intentional wounding in PAOO technique “tricks” the body by signaling local micro-fracture level microstrain and regional acceleratory phenomena (increased turnover and demineralization, i.e. transient osteopenia) is initiated. In other words, PAOO patient tissues go into hyper-activity in order to bring excessive microstrain back to steady state homeostatic levels which provide the orthodontist with the golden opportunity to accelerated tooth movement. The lesson learned from wound healing is that tensional readiness and the remarkable ability for maxillofacial tissue to accommodate to changes in tissue tension can be used to accelerate tooth movement. The host response is remarkably local and so PAOO surgery is used strategically to move certain teeth or tooth groups. Applying tensional integrity concept explains all variations in individual patient response to treatment and all experimental data from accelerated tooth movement investigations. The prevailing pressure-tension concept does not clearly explain the tooth movement phenomena and a PDL cell-mediated focus needs revisiting.

Keynote Forum

Diego Lops

University of Milan, Italy

Keynote: Real Esthetics of the Frontal Area: Mith or Reality?
Dentistry 2017 International Conference Keynote Speaker Diego Lops photo
Biography:

Abstract:

The patients high demanding expectations are actually to be carefully considered by the clinicians for a correct treatment plan in the treatment of anterior areas. Several new components are available for the manufacturing of implant abutments, crowns and veneers. These materials can by provided with cad-cam solutions (titanium, gold-hue titanium, zirconia), while ceramic veneers can be heat-pressed with 0.2-0.3 mm of thickness; such prosthetic solutions have to be considered as a part of a global esthetic treatment plan aiming to the armony of the whole frontal area.

Nevertheless, before the prosthetic resolution of the high demanding clinical case, a correct surgical treatment should be followed; an adequate implant selection, a correct 3D implant placement, a correct soft tissues management will be crucial to finalize the treatment with the proper prosthetic solution.

The surgical and prosthetic workflow will be carefully described by following the data available in the international literature.

Keynote Forum

Les Kalman

Western University, Canada

Keynote: Digitizing the facebow: A communication tool for implantology
Dentistry 2017 International Conference Keynote Speaker Les Kalman photo
Biography:

Les Kalman is an assistant professor in restorative dentistry and Chair of the DOCS program at the Schulich School of Medicine & Dentistry at Western University. The Dental Outreach Community Service (DOCS) program is a component of the senior dental curriculum that provides free dentistry to those with no other economic means. Kalman’s research focus includes medical devices & technologies relevant to clinical dentistry, with the intent of short-term industry translation. He has developed and translated what is now the Max Align, available through Whip Mix. He is also the founder and President of Research Driven, a corporation that manages intellectual property related to medical device technology. Kalman has authored articles ranging from pediatric impression to immediate implant surgery in Canadian and International journals. He is a member of the ITI, AO, AAID and the ICOI. He has been recognized as an Academic Associate Fellow (AAID), Fellow, Master and Diplomate (ICOI) and will be receiving the Schulich Alumni of Distinction Award in October. In his spare time, Kalman enjoys photography as an accredited MotoGP photojournalist.

Abstract:

Communication between the clinician and technician has been an ongoing problem in dentistry. To help improve the issue, a dental software application has been developed – the Virtual Facebow App. It is an alternative to the traditional analogue facebow (AF), used to orient the maxillary cast in mounting. Comparison data of the two methods indicated that the digitized virtual facebow provided increased efficiency in mounting, increased accuracy in occlusion and cost. Occlusal accuracy, lab and total time were statistically significant (P<0.05). The virtual facebow (VF) provides a novel alternative for cast mounting and another tool for clinician-technician communication.

Dentistry 2017 International Conference Keynote Speaker Eriberto Bressan photo
Biography:

Eriberto Bressan has obtained his Graduate of Dentistry and Dental Prosthesis Program in 1994 with top grades and Honors specialized in Orthodontics in 2001 at the University of Padua. He is the Scientific Head and Lecturer of the Master’s in Osseointegrated Implantology Advanced Course at the University of Padua and also the Specialization Course: Computer-guided implant surgery, at the University of Padua. He is the Director of Research Dentistry centre at University of Padua and has obtained PhD in Molecular Biology and Biotechnologies. He serves as the Chair of Periodontology and Implantology at the University of Padua (Italy) and also as a Speaker at National Congresses. He is the author of numerous publications in Italian and international research journals.

Abstract:

Nowadays, dental implantology is a reliable technique for treatment of partially and completely edentulous patients. The achievement of stable dentition is ensured by fixed dental prostheses. Morse taper system can provide fixed retention between implants and dental prosthesis without cement or screw. This system presents advantages both for clinician and patients, in term of time, cost and biological point of view. This prosthesis is fixed for patient but easy to remove for dentist and this system could help to maintain the health of soft peri-implant tissue. Actually, data on both in vitro and clinical performance of Cone-Morse retention are available, to confirm such trend on alternative of implant-supported restoration.

  • Oral and Dental Health
Biography:

Simone C H Regalo is a Titular Professor in the Department of Morphology, Physiology and Basic Pathology, RibeirãoPreto Dental School, University of São Paulo. She is leader of the CNPq research groups: Electromyography and the Multidisciplinary Center for Research in Bone Tissue. She has published more than 30 papers in reputed journals and has been serving as an Editorial Board Member of repute.

Abstract:

Statement of the Problem: Development of dental occlusion is a prerequisite for the success of any dental intervention.

Aim: The objective of this study was to evaluate the EMG activity of masticatory and perioral muscle; mandibular mobility; maxilla and mandible strength and tongue pressure in children with need treatment orthodontic.

Methodology & Theoretical Orientation: 64 children were selected and divided into three groups judged by the Index of Orthodontic Treatment Need (IOTN) criteria: GI: grade 1 (n=26; mean age 8.00±0.44), GII: grade 2 (n=28; mean age 8.89±0.44, n=26) and GIII:grade 3 (n=10; mean age 8.00±0.59) This study was approved by the Ethics Committee in Research of the School of Dentistry of RibeirãoPreto, University of São Paulo. Assessment of muscles activities were performed by EMG recordings of the right masseter (RM), left masseter (LM), right temporal (RT), left temporal (LT), orbicularis oris muscle, upper segment (right and left side) during rest, right and left laterality, maximum voluntary contraction with and without Parafilm M® and protrusion. Surface EMG was performed using TrignoTM Wireless (System Delsys). T-Scan® III Occlusal Analysis System was used to evaluate the intensity of the maxilla and mandible strength by maximum voluntary contraction. Tongue pressure was evaluated by Iowa Oral Performance Instrument (IOPI). The mandibular mobility was measured using a calliper.

Findings: The data obtained were tabulated and subjected to statistical analysis (SPSS 22.0; ANOVA; P<0.05). EMG activity was significant for rest: RM [(I= 0.08±0.01), (II=0.08±0.01), (III=0.24±0.09]; RT [(I=0.15±0.02), (II=0.16±0.03), (III=0.33±0.10]; protrusion: LT [(I=0.11±0.01), (II=0.14±0.02), (III=0.24±0.08]; right laterality: RM [(I=0.10±0.01), (II=0.16±0.03), (III=0.43±0.10]. There was no statistically significant difference for EMG activity of the orbicularis oris muscle, tongue pressure, mandibular mobility and maxilla/mandible strength.

Conclusion & Significance: The authors concluded that children in grade 3 (IOTN) showed

hyperactivity of mastication muscles and reduction in the pressure tongue.

Biography:

Shinichi Arakawa has graduated from Dental School, Tokyo Medical and Dental University in 1986. He has completed his PhD from Tokyo Medical and Dental University and Post-doctoral studies from University of Texas, Health Science Center at San Antonio and State University of New York at Buffalo. He is the Professor of Department of Lifetime Oral Health Care Science, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University.

Abstract:

Peri-implantitis are chronic inflammatory diseases caused by microorganisms residing in sub-gingival bio-film. Elimination of pathogen-containing bio-films remains the primary goal of the treatment for these diseases. The topical use of a low-cost, broad-spectrum antiseptic agent with low potential for adverse reactions is also preferable in treating peri-implantitis. Ozone (O3) is attracting attention as a possible alternative antiseptic in the dental field as well as food industries. The high stability of Ozone Nano-Bubble Water (NBW3) allows for bottling and use as a disinfectant solution. A nano-bubble is less than 100 nm in diameter, and is produced by the collapse of a micro-bubble (≤50μm in diameter) in an electrolyte solution. NBW3 retains ozone gas in the form of nano-bubble, and therefore can exert anti-microbial activity for more than 6 months if it is protected against exposure to ultraviolet rays. We have used NBW3 to the peri-implantitis patients. Clinical parameter indicated that surgical treatment was necessary according to the Cumulative Interceptive Supportive therapy (CIST). Two kinds of procedures were applied to this patient. One was mechanical plaque control and the other one was a chemical plaque control (sub-gingival irrigation) with NBW3 by using WaterPikTM. Twelve weeks later, the resorbed alveolar bone around the implants has been regenerated up to 4mm in height. These results suggested that the irrigation with NBW3 might be a promising adjunctive therapy for peri-implantitis. The use of NBW3 as an adjunct to the therapy for peri-implantitis would be promising.

Biography:

Abstract:

The aim of this study was to describe the intensive care unit (ICU) nurses’ knowledge, attitude, and practice of mouth care for their patients. This is a cross sectional hospital based study. A total of 154 ICU nurses were randomly selected from seven government hospitals in Khartoum state and were invited to take part in this study. 97.4% of ICU nurses had high knowledge of the importance of mouth care for ICU patients and similarly for the priority of mouth care. However, only 20% of nurses were found to apply good practice. 64.5% of the nurses received training in mouth care provision, and (81%) indicated that further training would be beneficial. The oral care practice of ICU nurses ranged between average among 57% and poor among 23%. The study highlighted the need for setting of ICU protocols and adoption of advanced training for ICU nurses.

Biography:

Prof. Dr. Simone Cecilio Hallak Regalo is titular professor in the Department of Morphology, Physiology and Basic Pathology, Ribeirão Preto Dental School, University of

São Paulo. She is leader of the CNPq research groups: Electromyography and the Multidisciplinary Center for Research in Bone Tissue. She has published more than

30 papers in reputed journals and has been serving as an editorial board member of repute.

Abstract:

Statement of the Problem: The dentition phases are associated with craniofacial growth and functions of the stomatognathic system. The objective of this research analyzed dentition phases by electromyographic activity, maxilla/mandible strength, tongue pressure and mandibular mobility. Methodology & Theoretical Orientation: 64 children were divided into three groups judged by the dentition phases: DG: deciduous dentition (mean age 4.65±0.21), MG: mixed dentition (mean age 8.30±0.28) and PG: permanent dentition (mean age 11.33±2.25) This study was approved by the Ethics Committee in Research of the School of Dentistry of Ribeirão Preto, University of São Paulo. Assessment of muscles activities were performed by EMG recordings of the right masseter (RM), left masseter (LM), right temporal (RT) and left temporal (LT) during rest, right and left laterality, maximum voluntary contraction with and without Parafilm M and protrusion. Surface EMG was performed using Trigno Wireless (Delsys). T-Scan III Occlusal Analysis System was used to evaluate the intensity of the maxilla/mandible strength by maximum voluntary contraction. Tongue pressure was evaluated by IOPI and the mandibular mobility (maximum opening of the mouth, laterality and protrusion) was measured using a calliper. Findings: The data obtained were tabulated and subjected to statistical analysis (SPSS 22.0; ANOVA; P<0.05). Statistically significant differences were found for mandibular mobility at maximum mouth opening [(DG=41.50±1.60), (MG=46.67±0.81), (PG=49.33±2.36)]. There was no statistically significant difference for EMG activity, maxilla/mandible strength and tongue pressure. In the EMG activity, the deciduous dentition presented higher values during protrusion (RM; LM; RT), right laterality (LM; RT) and left laterality (LM). The mixed dentition presented higher values at rest to all muscles and the permanent dentition showed higher value at maximum voluntary contraction. In the tongue pressure the permanent dentition presented higher value. Conclusion & Significance: There is relationship between the phases of the dentition with of the stomatognathic system functions.

Biography:

Victor Edson Rogerio is a Dentist who has worked in a group, taking care of children, who were undergoing a live transplantation program. The aim of the group was to assist those children and prepare their mouths for the surgery, and avoid infections from the oral cavity; which could interfere in the systemic health, or even lead to the graft loss, and patient death. This publication is part of the research project, he has accomplished for the master degree program.

Abstract:

Statement of the Problem: The cholestatic liver disease (CLD) leads to systemic metabolic consequences, causing comorbidities of difficult treatment and high mortality. If it does not have an early diagnostic, the only chance of patient’s survival is liver transplantation. The progression of a persistent CLD is associated to clotting disorders and increasing of the infections risk. These patients are usually subjected to multiple blood collections by venipuncture to monitor the progression of their liver disease, but these morbidities can become an ordinary blood collection, by venipuncture, very threatening to these patients. CLD patients’ have shown greenish tooth due to the intrinsic and progressive deposition of bilirubin, which is a porphyrin. In those circumstances, if it were possible to correlate the deposition of bilirubin with progression of the disease by a noninvasive method, that would be of a great value in the clinical management of the CLD patients.

Methodology & Theoretical Orientation: After confirming the capacity of DIAGNOdent to measure varying bile concentrations in plaster blocks, a cholestatic liver disease model was studied to detect increasing bilirubin impregnation in the teeth of rats. Wistar-EPM rats (n ¼ 50) were divided into three groups: (1) BDL: rats submitted to bile duct ligation (BDL); (2) Naıve: rats without procedure; and (3) Sham: rats submitted to laparotomy without BDL (n ¼ 10/period/group). The rats’ teeth were monitored with the use of DIAGNOdent

before the procedure and at days 10 and 50 following surgery. Serum bilirubin was also monitored.

Findings: Tests in vitro showed that DIAGNOdent detected bile in plaster blocks according to its concentration. BDL promoted progressive liver dysfunction, with death occurring approximately 50 days later. DIAGNOdent values obtained on teeth showed correlation with the progression of serum hyperbilirubinemia.

Conclusion & Significance: The tooth was found to be a good tissue for noninvasively monitoring the progression of bilirubinemia in cholestatic liver disease in rats by using DIAGNOdent.

Kishan M Sheth

King’s College London Dental School, UK

Title: Periodontitis and cancer: Does a link exist?
Biography:

Kishan M Sheth has published in several internationally renowned dental magazines. His work has recently been accepted into his first international peer reviewed journal, the Journal of Dental Health, Oral Disorders and Therapy. He has presented at 2 national conferences and has also lectured alongside PhD level students in the past for the London Materials' Society on the topic of MI dentistry. He was recently asked to give interviews for the British Dental Journal and Dental Town. Over the past two years, he has been working on a publication with Dr. Mandeep Ghuman entitled, 'Periodontitis and Cancer: Is there a link?'

Abstract:

The purpose of this presentation is to carefully analyse the research findings to date regarding a potential link between periodontitis and carcinogenesis; to evaluate, critically review and explore the variety of potential study confounders and study criteria differences which suppress the accuracy and validity of the relationship claims being made; to gain an appreciation of the biological plausibility of mechanisms which could be underpinning the relationship between the two diseases; and finally to conclude whether the current level, findings and quality of research is accurate in supporting the existence of the periodontitis – cancer link. I will assess the potential link between periodontitis and several cancerous tumour types, and analyse the evidence regarding the biological plausibility for the potential association between periodontitis and cancer.  The strongest association is present between periodontitis and oral cancer, since each of the three studies looked into show a statistical link between both diseases. The International burden of cancer has risen every year, a trend that has been paralleled by the increase in periodontitis cases. Research undertaken by GLOBOCAN (2012) states there were 7.6 million global cancer cases in 2008, and in 2012 there were 14.1 million global cancer cases, an increase of 84%. Although there is a lack of recent statistical data related to periodontitis cases, between the years 1997 and 2005, there was an increase of 27% of adults aged between 35 and 44 who had periodontal pocket depths greater or equal to 4 millimetres

  • Oral Implantology
Biography:

Abstract:

Background: A special form of reconstruction of bone, especially changing the vertical structure of the maxillary sinus floor in the upper jaw and the establishment of the mucous membranes of sinusitis purpose of dental implant is called sinus-lift. Distance-maxillary sinus is often so low that an implant cannot be included stable long enough. With the incorporation of bone material or bone grafting, maxillary sinus floor, 'grow' and that this level can be implanted safe. Sinus-lift distinguishes extern and intern.

Purpose: The purpose of this paper is to show how we can perform fenestration of sinus without damaging the membrane of the maxillary sinus mucosa respectively. So it is very important that the membrane without damaging the remains to preserve the anatomical structure of sinusitis and its airspace.

Material & Methods: Cutting the bone from the piezo-surgery without damaging the soft tissue in surgery is a challenge, especially to compensate for the loss of bone extensive alveolar process. Implantologs use various techniques to increase augmentation bone-grafting. Piezotom enables the implementation of sophisticated procedures as osteotomic, osteoplastic for the opening of the jaw in sagital direction or elevation of the membranes of the maxillary sinus. With the 28-36 kHz, the frequency is chosen so that ultrasound piezotom acts exclusively in the solid tissues.

Conclusions: Once that is done, elevation of the sinus membrane follows its partial filling of the bone material in order to rebuild the bone. Good access of additional instruments and limiting the amplitude of vibration work together for more accurate cutting of bone.

Biography:

Simon Wright has been a principal partner of Glencairn Dental group of practices since 2002.  He is the Founding Director of both Dental Implant Resource Ltd and Implant Centres of Excellence Ltd. in Implant Dentistry and he did his MSc in Dental Implantology. He is a programme and clinical lead for Dental Implantology at Edge Hill Unversity (UK). His current research interest areas are: Patient Related Outcome Measures (PROM), Peri-Implant Disease, and Human Factors and Implant Dentistry. He has gained national recognition for his work developing tools to measure PROM in dentistry.  He has written the algorithms that have been adopted as the standard protocols for the treatment of Peri-Implant disease.  He has established a recognised referral centre for the treatment of both Mucocitis and Peri-Implantitis. He is currently the clinical lead, investigating the outcome of a series of case studies. He has a keen interest in surgical performance and has been invited to participate in the first ‘European Congress about Human Factors and Medicine’ in Paris. He is the Academic Director of the ICE Hospital and ICE Ltd (Implant Centres of Excellence).  This consists of an educational academy; the ICE institute, a network of clinics; the referral centres, and ICE Association; support and interaction.

Abstract:

Dental implants are a common treatment modality to replace missing teeth, and high survival rates in several 10 years follow-up studies, which have encouraged their widespread prescription. However, with an increase in the provision of dental implants, there is an increase in the number and frequency of patients that are affected by complications. This is further complicated by different stages of treatment often being carried out by multiple clinicians. This multi-disciplinary approach is encouraged, however it makes follow up and auditing treatment outcomes more challenging. In particular, when the maintenance and review is undertaken by GDP’s with little or no training in the detection of peri-implant complications and disease implant complications, both mechanical and biological can eventually lead to bone loss around the implant and ultimately implant loss. Hence it is essential to detect and treat complications early, and although the data is limited for the treatment of peri-implant complications, there is evidence that an early diagnosis will allow an early intervention and a more predictable resolution. If early signs are missed, in particular with reference to peri-implant mucositis, this will develop into peri-implantitis which is more complicated and less predictable to treat. This presentation investigates the methods, and presents Dr Wright’s research for monitoring implants in the short and the long term, and to discuss if the patient can play an active role in this monitoring programme.

Biography:

Abstract:

Patients with atrophy of the maxillae, generally the elderly, are usually difficult to handle clinically, mainly due to the lack of retention, stability, and masticatory effectiveness of the total removable prosthesis. A new technique involving osseointegrated implants that are parallel to each other and arranged in the intermaxillary suture seems to provide great advantages over the current options for oral rehabilitation. This technique is quick and effective, being performed with local anesthesia and without a bone graft, and still presents low morbidity and cost.

  • Diagnosis and Prevention of Oral Disease

Session Introduction

Sura Ali Ahmed Fuoad Al-Bayati

Gulf Medical University, UAE

Title: Dental management of patient with Multiple sclerosis
Biography:

Sura Ali Ahmed Fuoad Al-Bayati has done his Doctoral Degree (PhD) and Master’s Degree (MDS) in Oral Medicine from Baghdad University, Iraq. He did his Bachelor’s Degree of Oral and Dental Medicine and Surgery (BDS) from Baghdad University, Iraq. He did his Diploma in Health Profession Education from Gulf Medical University, UAE.

He is a faculty of College of Dentistry, since 1988 in Baghdad University, Iraq, till 2006, up to date in Gulf medical university, UAE. He is an Academic Associate Dean at College of Dentistry, Gulf Medical University, since 2010. He is an Associate Professor of Oral Medicine and the Head of Basic Dental Sciences at College of Dentistry, GMU. He has many publications in Dentistry and is the Member of many Committees in GMU and College of Dentistry.

Abstract:

Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system. MS makes it difficult for the nerve cells in the brain and spinal cord to communicate effectively with one another. The symptoms of MS are of a wide range, and may resemble symptoms of many other disorders, and other dental problems that need especial care. In addition to poor muscle control, a patient with MS experiences a disability to perform oral hygiene measures. The treatment for multiple sclerosis includes taking medications to slow the progression of the disease, which may have a side effect on the oro-facial structures. Management of such dental and oral patient needs a team work and appropriate care to delay disease progression and maintain an optimal quality of life as long as possible.

Marie T Fluent

Organization for Safety, Asepsis, and Prevention, USA

Title: Antibiotic resistance and antibiotic stewardship
Biography:

Marie T Fluent, DDS is a graduate of the University of Michigan, School of Dentistry.  She has practiced General Dentistry in a private practice setting for 25 years.  She is currently an infection control consultant and an educational consultant for OSAP (Organization for Safety, Asepsis and Prevention).  She has written numerous peer reviewed articles regarding infection control in the dental setting, OSHA compliance and antibiotic stewardship in dentistry.

Abstract:

Misuse and overuse of antibiotics have given rise to bacteria fully adapted to the antibiotics designed to kill them. Antibiotic resistance is now a real and serious global health threat.  This lecture describes how antibiotic resistance occurs and discusses the crucial need for a proper antibiotic stewardship program in the dentistry.  Dentist’s knowledge and behaviors regarding antibiotic use will be addressed; challenges faced and clinical tips for responsible antibiotic prescribing will be discussed.

Biography:

Khushboo Rastogi has her expertise in the branch of Periodontology and Implantology and her passion and hard work has resulted into creating mass awareness among patients. Her dedication has embarked her profile as working head of her department in a reputable medical college. Though her experience is of short duration but her keenness’ and zeal to learn is her response to not leave any stone unturned.

Abstract:

Several cases reports are reported in our daily dental practice of unknown swellings developed overnight or since several months. Here we are trying to focus on the cases of different ages i.e. during mixed dentition and permanent dentition and their correlation to patient’s negligence and unawareness. These patients presented to the Out-Patient Department of Dentistry in Saraswathi Institute of Medical Sciences with the chief complaint of oral swelling which was described as painless but liked a knot; in the respective lower jaw since 15 days, 1 month and 2 month respectively. Among them there was one patient who reported of pain while eating in the lower left jaw but was unaware of its cause, duration and lack of time protocol. Hence we could correlate that cystic swellings and negligence of patients are directly correlated.

  • Therapy and Treatment

Session Introduction

Vallabh Chawla

Dr. G.D. Pol Foundation’s Yerala Medical Trust Dental College and Hospital, India.

Title: Treatment of Tobacco Induced Lesions: Case Reports
Biography:

Vallabh Chawla, Post Graduate student, Department of Oral Medicine and Radiology, Dr. G.D. Pol Foundation’s Yerala Medical Trust Dental College and Hospital, Kharghar, Navi Mumbai, India. (vallabh.chawla@gmail.com)

Deepa Das, Professor and Head of Department, Department of Oral Medicine and Radiology, Dr. G.D. Pol Foundation’s Yerala Medical Trust Dental College and Hospital, Kharghar, Navi Mumbai, India.

Abstract:

Approximately 50% of the individuals do not have a routine dental check-up and are unaware of their oral health condition. Most Oral Cancers appear to arise in apparently normal mucosa, but often preceded by premalignant lesions like Leukoplakia (speckled/ verrucous), Erythroplakia and premalignant conditions like Oral Submucous fibrosis due to the use of tobacco in both smoking and smokeless form. Leukoplakia is a non-scrapable potentially malignant disorder that cannot be characterized clinically or pathologically as any other disease. Oral Submucous fibrosis (OSMF or OSF) is a chronic, complex, premalignant (1% transformation risk) condition of the oral cavity, characterized by juxta- inflammatory reaction and progressive fibrosis of the submucosal tissues where he jaws become rigid to the point that the person is unable to open the mouth. Since most of these pre-malignant lesions/ conditions are symptomless, patients are ignorant about their presence in the oral cavity. Delay in detection, diagnosis and treatment of such lesions can lead to malignant transformation and later show a propensity to become cancerous as time progresses. Management includes cessation of habit, chemo-preventive medications, surgical excision, laser ablation, and cryotherapy.  This paper will highlight interesting cases on oral cancer screening, treatment of leukoplakia using cryotherapy and diode laser ablation therapy and treatment of Oral submucous fibrosis using chemo-preventive medications and intra-lesional injections on patients reporting to the institute with such pre-cancerous lesions and conditions. Patients were first advised to quit the habit followed by treatment and timely follow ups.

Akhilanand Chaurasia

King George’s Medical University, India

Title: Chronobiologically modulated chemotherapy in oral cancer
Biography:

Akhilanand Chaurasia is an Associate Professor and Consultant at King George Medical University, Lucknow and has dedicated meticulous efforts and supreme services pertaining to oral medicine and oral biology. He has an elite academic record. He is graduated from King George’s Medical University in 2005 and completed his Post-graduation from University of Kerala in 2009. He has obtained Diploma in Healthcare Biomedical Waste Management. He has remarkable credit of contributing to academics by publishing 54 manuscripts and peer reviewers of more than 150 international journals. He also served as an Editor-In-Chief of 2 national journals, Associate Editor of 1 international journal, Editor of 10 international journals, Editorial Board Member of 17 international journals and an Ambassador of European Association of Cancer Research. He is a fellow of many prestigious and pristine organizations of dentistry and also a member of 30 international organizations. He is active guide and mentor for Post-graduate programs. Currently, he is pursuing PhD in Chronobiology of Head and Neck cancer.

Abstract:

Chronobiology is the study of the temporal relationships of biological phenomena. All living things evolved in a milieu characterized by constant change based upon the cyclic relationships of the sun, earth and moon. The circadian periodicity is genetically retained by all living organisms. Circadian organization is such a basic property of life that derangements may have lethal consequences. Mammalian circadian rhythms result from a complex organization involving molecular clocks within nearly all “normal” cells and a dedicated neuroanatomical system which coordinates the so-called “peripheral oscillators.” The core of the central clock system is constituted by the su­prachiasmatic nuclei that are located on the floor of the hy­pothalamus. This circadian organization is responsible for predictable chang­es in the tolerability and efficacy of anticancer agents. The circadian rhythm dependent chemotherapy provides indirect evidence for time-dependent variability of the response of the human and murine to anticancer drugs. Doxorubicin, cisplatin, 5-fluorouracil and FUDR have been studied in oral cancer for their circadian pharmacodynamics and toxicology. The outcome of these studies clearly concluded that circadian dependent administration of anticancer drugs reduces drug toxicity and allows substantial increase in the maximally tolerated dose which results in better treatment efficacy and greater comfort for oral cancer patients. Thus chronobiologically modulated chemotherapy hold promising results in treatment of oral cancer and other cancer with increased efficacy and decreased toxicity. In coming years the future of cancer treatment lies in circadian rhythm dependent chemotherapy.